Explore the science of bioprinting, a type of 3D printing that uses bioink, a printable material that contains living cells. -- There are currently hundreds of thousands of people on transplant lists, waiting for critical organs like kidneys, hearts and livers that could save their lives. Unfortunately, there aren’t enough donor organs available to fill that demand. What if, instead of waiting, we could create new, customized organs from scratch? Taneka Jones explores bioprinting, a new branch of regenerative medicine. Lesson by Taneka Jones, directed by Hype CG. Animator's website: https://www.hype.cg Sign up for our newsletter: http://bit.ly/TEDEdNewsletter Support us on Patreon: http://bit.ly/TEDEdPatreon Follow us on Facebook: http://bit.ly/TEDEdFacebook Find us on Twitter: http://bit.ly/TEDEdTwitter Peep us on Instagram: http://bit.ly/TEDEdInstagram View full lesson: https://ed.ted.com/lessons/how-to-3d-print-human-tissue-taneka-jones Thank you so much to our patrons for your support! Without you this video would not be possible! Sydney Evans, Latora Slydell, Oyuntsengel Tseyen-Oidov, Noel Situ, Elliot Poulin, emily lam, Juan, Jordan Tang, Kent Logan, Alexandra Panzer, Laura Cameron Keith, Jen, Ellen Spertus, Cailin Ramsey, Markus Goldhacker, Leora Allen, Andras Radnothy, Chris, Arpita Singh, Vijayalakshmi, Marc Bilodeau, Peng, Tzu-Hsiang, paul g mohney, Maya Toll, Sebastian Regez, Bruno Hannud, Andreas Voltios, Shubham Arora, Ugur Doga Sezgin, Akinola Emmanuel, Kyanta Yap, Ricardo Rendon Cepeda, Ana Maria, Benjamin & Shannon Pinder, Ernest Chow, Bela Namyslik, Alan Froese, Anika Westburg, Nick Cozby, Shawar Khan, Michael Braun-Boghos, Rohan Gupta, Elizabeth Cruz, Yujing Jiang, Sarah Lundegaard, Vladimir Ivanchenko, Georg Gusewski, Rohit Lodha, Erica Zhuang and Aaron Henson.

This breathing air sac model serves as a proof of concept in a field where 3D printing vasculature has been one of the biggest challenges. Why This 3D Light Printer Is a HUGE Game Changer https://www.youtube.com/watch?v=Yy-d5VVZlxQ Read More: Multivascular networks and functional intravascular topologies within biocompatible hydrogels https://science.sciencemag.org/content/364/6439/458 "Solid organs transport fluids through distinct vascular networks that are biophysically and biochemically entangled, creating complex three-dimensional (3D) transport regimes that have remained difficult to produce and study." 3D Bioprinting for Organ Regeneration https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313259/ "Regenerative medicine holds the promise of engineering functional tissues or organs to heal or replace abnormal and necrotic tissues/organs, offering hope for filling the gap between organ shortage and transplantation needs." ____________________ Elements is more than just a science show. It’s your science-loving best friend, tasked with keeping you updated and interested on all the compelling, innovative and groundbreaking science happening all around us. Join our passionate hosts as they help break down and present fascinating science, from quarks to quantum theory and beyond. Seeker explains every aspect of our world through a lens of science, inspiring a new generation of curious minds who want to know how today’s discoveries in science, math, engineering and technology are impacting our lives, and shaping our future. Our stories parse meaning from the noise in a world of rapidly changing information. Visit the Seeker website https://www.seeker.com/videos Elements on Facebook https://www.facebook.com/SeekerElements/ Subscribe now! http://www.youtube.com/subscription_center?add_user=dnewschannel Seeker on Twitter http://twitter.com/seeker Seeker on Facebook https://www.facebook.com/SeekerMedia/ Seeker http://www.seeker.com/

A record amount of money is spent developing new drugs, but drug approval rates are declining and many fatal diseases are left untreated. A big reason behind this is often times current drug testing methods including animal testing don’t accurately predict the human response to drugs. What if we can 3D print living human tissue to test new drugs and study disease? Tamer Mohamed talks about how 3D printing human tissue will allow us to develop better, safer, and cheaper drugs while reducing our reliance on animal testing. Beyond drug development, Tamer imagines a future where replacement organs are 3D printed using a patient’s own cells, avoiding organ wait lists and the risk of rejection. Tamer Mohamed is a biomedical engineer, innovator, and entrepreneur. He is President and CEO of Aspect Biosystems Ltd., a biotechnology company operating at the leading edge of 3D bioprinting and tissue engineering - www.aspectbiosystems.com. Tamer can be reached at tamer@aspectbiosystems.com This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx

Organovo’s bioprinting process centers around the identification of key architectural and compositional elements of a target tissue, and the creation of a design that can be utilized by a bioprinter to generate that tissue in the laboratory environment. Once a tissue design is established, the first step is to develop the bioprocess protocols required to generate the multi-cellular building blocks—also called bio-ink—from the cells that will be used to build the target tissue. The bio-ink building blocks are then dispensed from a bioprinter, using a layer-by-layer approach that is scaled for the target output. Bio-inert hydrogel components may be utilized as supports, as tissues are built up vertically to achieve three-dimensionality, or as fillers to create channels or void spaces within tissues to mimic features of native tissue. The bioprinting process can be tailored to produce tissues in a variety of formats, from micro-scale tissues contained in standard multi-well tissue culture plates, to larger structures suitable for placement onto bioreactors for biomechanical conditioning prior to use.